Д. Байгуйсова

https://orcid.org/0000-0001-5724-7707

Найдено статей: 4

  • Survival analysis and characteristics of pancreatic adenocarcinoma based on msct data of 216 cases (Выпуск № 1, 2025)

    D. Baiguissova, Y. Akhmetov, B. Duisenbayeva, A. Mukhamejanova,, G. Battalova, Y. Kalshabay, A. Kabidenov, A.,, M. Doskhanov Sadykova
    2025-03-31
    46–53
    Аннотация

    Background. Pancreatic adenocarcinoma is an aggressive cancer with a poor prognosis and increasing global incidence. Early diagnosis is challenging, as it is often detected at advanced stages. Imaging, particularly contrast-enhanced Multispiral Computed Tomography, plays a crucial role in diagnosing, assessing resectability, and monitoring treatment response. This study aimed to analyze Pancreatic adenocarcinoma characteristics, including tumor location, metastasis, resectability, and postoperative outcomes, using Multispiral Computed Tomography. Methods A retrospective review of 216 Pancreatic adenocarcinoma cases from 20222024 was conducted. All patients underwent bolus contrast-enhanced Multispiral Computed Tomography, and diagnoses were confirmed by histology. Key patient parameters analyzed included age, gender, tumor location, metastases, and surgical outcomes. Results The group comprised 50.9% women and 49.1% men. The majority of tumors were located in the pancreas head (72.2%), followed by the body (13.9%), tail (3.7%), and multiple sites (10.2%) (p<0.05). Metastases were observed in 50% of patients, with the liver being the most common site (p<0.05). Radical surgery was performed in 41 patients (19%), while 66 patients (30.5%) underwent palliative procedures. The mean life expectancy among deceased patients was without surgery 110 days, after radical resections 247 days, after palliative interventions 118 days. Conclusion Pancreatic adenocarcinoma remains a highly fatal disease, particularly at advanced stages. Metastasis significantly worsens prognosis, reducing survival rates. Tumor location influences prognosis, with body and tail tumors having better outcomes. Surgery improves survival, and early diagnosis is critical. Contrast-enhanced Computed Tomography is essential for evaluating pancreatic tumors but should be complemented with other diagnostic methods for enhanced accuracy.

    Ключевые слова

    Pancreatic Adenocarcinoma, Metastases, Survival, Surgical Treatment, Computed Tomography

  • A new perspective on diagnosis: the potential of CT perfusion in chronic liver disease (literature review) (Выпуск № 3, 2024)

    G. Battalova, D. Baiguissova, E. Kalshabay, A. Mukhamejanova, A. Mukanova, D. Nagimova, A. Kabidenov, B. Abzhaparova, B. Baimakhanov
    2024-09-30
    98–107
    Аннотация

    : the aim of this study is to analyze the current advances of CT perfusion in the diagnosis of liver disease. Liver fibrosis is a characteristic feature of chronic liver disease and is confirmed by liver biopsy, which is an invasive method. Morphologic parameters of cirrhosis are evaluated by conventional imaging techniques such as ultrasound (US), computed tomography (CT) and magnetic resonance imaging (MRI). Additional studies of new imaging modalities are needed for earlier diagnosis, surveillance and accurate treatment, CT perfusion has several advantages by examining the arterial and venous blood flow of the liver, which gives a more complete picture of early functional changes in the liver. Despite the advantages of this method, the results of postprocessing in different stages of fibrosis and etiology of its development are not fully understood.

    Ключевые слова

    CT perfusion, liver fibrosis, liver cirrhosis, computed tomography, liver elastometry

  • Diagnostic accuracy of multispiral computed tomography in detecting and staging of esophageal and gastric cancer (Выпуск № 3, 2024)

    B.B. Baimakhanov, А.А. Shokebayev, K.M. Kanatov, D. Baiguissova, A. Abilseit, A. Kalibekova, A. Markelova, Y. Kalshabay, A. Mukhamedzhanova, N.Т. Orynbassar, T.A. Nazar
    2024-09-30
    19–25
    Аннотация

    Background. The sensitivity and specificity of multislice computed tomography is of great importance in the detection of gastric and esophageal cancer, and also expands the possibilities of preoperative staging using computed tomography.

    Materials and methods. A retrospective study at the A.N. Syzganov National Scientific Center of Surgery from 2022 to 2024, included 121 patients: 48 females (39.6%), 73 males (60.3%), with an average age of 60 years. Sensitivity, specificity were calculated to assess diagnostic accuracy. Esophageal and gastric cancer staging via computed tomography was done using the TNM classification and compared with esophagogastroduodenoscopy, pathohistological examination results.

    Results. The sensitivity of computed tomography was 96.49%, the specificity was 85.71%. Esophagogastroduodenoscopy showed a sensitivity of 79.75%, specificity of 95.24%.

    Conclusion. Computed tomography is highly informative, sensitive in detecting esophageal and gastric cancer, with superior diagnostic accuracy compared to esophagogastroduodenoscopy. Given the detection of esophageal and gastric cancer at T2 and T3 stages, along with the presence of distant metastases in some patients, implementing protocols for early diagnosis is advisable.

    Ключевые слова

    esophageal cancer, gastric cancer, adenocarcinoma, multispiral computed tomography, biopsy, histology

  • Диагностика рака поджелудочной железы: преодоление погрешностей и ошибок (се- рия случаев) (Выпуск № 2, 2024)

    Д. Байгуйсова, Д. Әуесбек, А. Мұқанова, Д. Нагимова, А. Сәлімбекова
    2024-06-28
    15–24
    Аннотация

    Диагностика злокачественных новообразований поджелудочной железы представляет собой сложную задачу, обремененную возможностью диагностических ошибок из-за сходства с другими патологиями, такими как панкреатит, нейроэндокринные опухоли и кистозные образования. Ключевым методом диагностики является мультиспиральная компьютерная томография с контрастным усиление, однако и этот метод имеет определенные ограничения, которые могут сказаться на точности диагностики.В ходе анализа клинических случаев были выявлены типичные ошибки, сопровождающиеся визуальными характеристиками, которые могут ввести в заблуждение при дифференциальной диагностике. Гиподенсивность и изменение структуры ткани, изменения в протоках или масс-эффект могут быть общими признаками как рака, так и панкреатита. Сопоставление визуальных признаков с клинической картиной и дополнительными методами помогает поставить более точный диагноз. Редкие патологии, такие как серозно-олигокистозная аденома и внутрипротоковая слизисто-папиллярная опухоль, могут также представлять собой дополнительные сложности для правильной диагностики из-за их необычных характеристик на сканах компьютерной томографии.Выводы исследования подчеркивают важность мультимодального подхода к диагностике злокачественных новообразований поджелудочной железы, включая использование различных визуализационных методов для обеспечения точного диагноза и выбора наиболее подходящей тактики лечения.

    Ключевые слова

    Протоковая Аденокарцинома Поджелудочной Железы, Инвазивный Внутрипротоковый Папиллярный Муцинозный Рак, Нейроэндокринная Опухоль, Компьютерная Томография, Поджелудочная Железа