M.A. Zhakubayev
https://orcid.org/0000-0001-8492-2958
Табылған мақалалар: 2
-
A Rare Case Of Congenital Portosystemic Shunt (Abernethy Malformation Type II) In A Child. Diagnosis, Endovascular Interventional Strategy, And Follow-Up (Шығарылым № 3, 2025)
Kozhamkul Alisher, Bolatkan Arlan, Abilkhanov Yerzhan, Onlasynov Aziz, Sapunov Alexander, Pazilov Sabit, Saduakas Almas, Zhakubayev Manat, Matkerimov Askar, Oraqbai Ernur2025-09-3010–17Аңдатпа
Congenital portosystemic shunt, also known as Abernethy malformation, is a rare vascular anomaly in which portal venous blood partially or completely bypasses the liver and enters the systemic circulation. This condition can lead to severe complications such as hepatopulmonary syndrome, hepatic encephalopathy, hypoxemia, and hyperammonemia. This article presents the first clinically confirmed and successfully treated case of Abernethy type II malformation in a child in Kazakhstan, who developed severe hepatopulmonary syndrome. A detailed description is provided of the diagnostic algorithm, angiographic evaluation, the endovascular intervention technique, and the patient’s clinical course over a five-year follow-up period. Shunt closure resulted in marked clinical improvement, including normalization of oxygen saturation (from 60% to 98%), reduction in blood ammonia levels, increased exercise tolerance, and enhanced quality of life. The findings support the effectiveness of an individualized, stepwise approach in the management of type II CPSS. The importance of early recognition of this condition is emphasized, particularly in pediatric patients presenting with unexplained cyanosis, hypoxemia, or signs of hepatic dysfunction. Endovascular techniques, due to their minimally invasive nature and high clinical efficacy, represent an optimal therapeutic strategy in pediatric practice.
Кілт сөздер
Abernethy malformation, hepatopulmonary syndrome, congenital portosystemic shunt (CPSS), transcatheter shunt closure
-
Stroke: a comprehensive overview of trends, prevention, and treatment (literature review) (Шығарылым № 3, 2024)
A.S. Shamshiev, Y.Y. Saduakas, M.A. Zhakubayev, A.Zh. Matkerimov, T.N. Demeuov, I. Omarkyzy, R.O. Makkamov, N.N. Yerkinbayev, A. Kozhamkul, D.M. Appazov, N. Begim, D.K. Davletov2024-09-3071–81Аңдатпа
A stroke is an emergency medical condition, commonly referred to as a cerebrovascular accident, occurs when the blood supply to the brain is interrupted, depriving brain tissue of oxygen and essential nutrients. This interruption can lead to rapid neurological impairment and, if not treated promptly, permanent brain damage or even death. Stroke is primarily categorized into two types: ischemic, resulting from arterial blockage, and hemorrhagic, caused by a ruptured blood vessel. Conditions such as acute cerebral circulatory disorder, atherosclerosis, and carotid artery stenosis are strongly associated with an increased stroke risk. Understanding these underlying factors is crucial for effective prevention, early detection, and management of stroke. Globally, stroke ranks as the second lead in cause of disability and mortality, disproportion at early affecting low-and-middle - income countries. Efforts in stroke prevention emphasizes the significance of early detection, management, promoting healthy lifestyles, and implementing legislative measures. The healthcare costs associated with stroke are substantial and projected to grow significantly. Socioeconomic factors and adverse working conditions also influence stroke incidence. Advancements in surgical revascularization techniques, such as carotid endarterectomy and stenting, have demonstrated efficacy in reducing stroke risk. Continuous research and development of optimal treatment strategies and monitoring protocols are essential for improving stroke outcomes and mitigating its global burden.
Кілт сөздер
stroke, acute cerebral circulatory disorder, carotid endarterectomy, carotid artery stenting, atherosclerosis
