S. Teipov

https://orcid.org/0000-0003-2376-0355

Articles found: 2

  • Fatty liver disease after pancreatoduodenectomy and total pancreatectomy (Issue № 1, 2025)

    S. Tileuov, A. Dzhumabekov, B. Baimakhanov, M. Doskhanov, S. Kaniyev, J. Ospan, Y. Yenin, M. Tursynbai
    2025-03-31
    20–28
    Abstract

    Pancreatoduodenectomy is the only treatment method for patients with pancreatic head and periampullary region tumors. It is known that some long-lived patients develop exocrine pancreatic insufficiency after surgery. One of the consequences of exocrine pancreatic insufficiency is fatty liver disease, which has been reported to occur in 7.8% to 40.0% of patients after pancreatoduodenectomy. We reported two clinical cases of patients who underwent pancreatoduodenectomy and total pancreatectomy for pancreatic head cancer and intraductal papillary mucinous neoplasm of the main pancreatic duct. After surgery, they developed rapidly progressive fatty liver disease with no history of liver disease, leading to death from liver failure 20 days and 3 months after surgery. Severe malnutrition caused by exocrine pancreatic insufficiency, postoperative eating disorders, and exacerbation of diabetes mellitus were the main factors contributing to the rapid deterioration of the condition. This clinical case highlights the possibility of developing life-threatening fatty liver disease with severe fibrosis after pancreatoduodenectomy and total pancreatectomy. Careful monitoring of liver status, regular nutritional assessment of patients, prophylactic replacement of pancreatic enzymes, and ensuring adequate nutrition are important.

    Keywords

    pancreatoduodenectomy, fatty liver disease, pancreatic cancer, liver failure, exocrine pancreatic insufficiency

  • FIRST EXPERIENCE OF LAPAROSCOPIC HEPATICOJEJUNOSTOMY FOR BILE DUCT STRICTURES (Issue № 2, 2024)

    M. Doskhanov, A. Khajiyeva, B. Baimakhanov, S. Kaniyev, M. Seisembaev, Z. Ospan, S. Teipov
    2024-06-28
    50–60
    Abstract

    Background. Bile duct injury is a potentially life-threatening condition characterized by high morbidity and mortality, which occurs as a result of erroneous manipulation during surgical intervention, such as incorrect identification of the ducts, improper clipping, or thermal injury. The aim of the study is to investigate the effectiveness of laparoscopic hepaticojejunostomy in patients with post-cholecystectomy bile duct injuries and compare it with traditional open techniques. Materials and

    Methods. A retrospective analysis of the results of laparoscopic and open hepaticojejunostomy in patients with bile duct injuries from 2017 to 2023 was conducted.

    Results. Laparoscopic surgery was performed on 28 patients, while open surgery was performed on 57 patients. Statistically significant differences were noted in the presence of external biliary fistula, diameter of the anastomosis, duration of the operation, postoperative complications, and postoperative period. There were no significant differences in the frequency of intraoperative complications.

    Conclusion. The laparoscopic approach in treating bile duct strictures classified as Strasberg E1 - E2 is safe and effective.

    Keywords

    Bile duct injury, cholecystectomy, laparoscopic hepaticoejunostomy, hepaticoejunoanastomosis