2. Results of gastrointestinal bleeding treatment in the republic of kazakhstan over 10 years

O.T. Ibekenov; A. E. Ayupov; A.N. Zhuraeva; B.B. Baimakhanov; S.А. Kaniyev; M.O. Doskhanov; A.O. Ibekenova

doi:10.35805/BSK2024III002

Authors

O.T. Ibekenov Syzganov National Scientific Center of Surgery, Almaty, Kazakhstan, Kazakh National Medical University named after S.D. Asfendiyarov, Almaty, Kazakhstan https://orcid.org/0000-0001-6605-6435
A. E. Ayupov Kazakh National Medical University named after S.D. Asfendiyarov, Almaty, Kazakhstan https://orcid.org/0009-0004-6635-4386
A.N. Zhuraeva Kazakh National Medical University named after S.D. Asfendiyarov, Almaty, Kazakhstan https://orcid.org/0009-0006-7568-7849
B.B. Baimakhanov Syzganov National Scientific Center of Surgery, Almaty, Kazakhstan, Kazakh National Medical University named after S.D. Asfendiyarov, Almaty, Kazakhstan https://orcid.org/0000-0003-0049-5886
S.А. Kaniyev Syzganov National Scientific Center of Surgery, Almaty, Kazakhstan, Kazakh National Medical University named after S.D. Asfendiyarov, Almaty, Kazakhstan https://orcid.org/0000-0003-3390-8931
M.O. Doskhanov Syzganov National Scientific Center of Surgery, Almaty, Kazakhstan, Kazakh National Medical University named after S.D. Asfendiyarov, Almaty, Kazakhstan
A.O. Ibekenova Nazarbayev University School of Medicine, Astana, Kazakhstan https://orcid.org/0009-0004-3222-3118
A. Ibekenova https://orcid.org/0009-0006-4575-8298

DOI:

https://doi.org/10.35805/BSK2024III002

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Abstract

Gastrointestinal bleeding (GIB) remains a significant cause of hospitalization and mortality worldwide, including in Kazakhstan. This retrospective study analyzes the incidence, treatment outcomes, and mortality of GIB in the Republic of Kazakhstan over a 10-year period (2014–2023) using data from 101,703 patients across 254 medical institutions. The study differentiates between non-variceal and variceal GIB, highlighting a 24.5% increase in non-variceal cases and a 45.1% increase in variceal cases due to higher rates of acute ulcerative lesions and liver cirrhosis, respectively. Men were disproportionately affected, accounting for 69.3% of cases, with the highest incidence in the 18-59 age group. Despite a 27.8% increase in GIB cases, overall mortality decreased from 7.8% in 2014 to 5.0% in 2023, largely due to advances in endoscopic hemostasis and critical care management. The mortality rate for non-variceal GIB decreased to 3.0%, while variceal GIB decreased from 23.8% to 13.6%. The results underscore the need for improved prevention, especially in high-risk populations using NSAIDs and anticoagulants, and in those with chronic conditions such as liver disease.

Keywords

gastrointestinal bleeding, incidence, mortality

References

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Published

2024-09-30

Issue

No. 3 (2024)

Section

Статьи