2. Effect Of Reperfusion To The Antioxidant Protection System Of Hepatic Tissue In Early Stage Of Ischemia
Downloads
Abstract
One of the actual problems of contemporary medicine is the restoration of the tissue structure that has been impaired. Because today, with the rapid development of medical technology, the pathologies called “inoperabel” were brought to life by organ transplantation. Liver cirrhosis, malignant tumors without metas-tasis, chronic renal failure, and so on. liver and kidney transplantation has become a therapeutic tool for the treatment of illness. The experiments were performed on head white rats. Experiments were carried out in accordance with the rules set out in Protocol No. 31 of the Bioethics Committee of 21 April 2008. All weighing procedures and experimental extraction on animals have been accomplished through inhalation anesthesia. Anesthesia was given to animals to form a liver ischemia model, and the abdominal cavity was opened at full disinfection. The right part of the artery entering the liver has been mobilized and taken to the liver. By using the ligature, a reperfusion pattern has been created to relieve the ischemia.
Keywords
Liver, pathology, tissue, ischemia
References
- Готе С.В. Трансплантация печени: клинические и хирургические аспекты //50 лекций по хирургии. Под ред. В.С.Савельева, М.: Триада – Х.
- Structural internal protein hydrosulfide groups (nmol / mq)
- Busuttil R.W., Klintmalm G.K. Transplantation of the liver – Elsevier Saunders, 2005. – 1485 p
- Феодоров В.Д., Вишневский В.А., Назаренко Н.А., и др. Основные осложнения обширных резекций печени и пути их предупреждения //Бюллетень, Сибирский медицины 2007, № 3, с.16-21
- Total antioxidant activity (cc). Surface and structural internal hydrosulfide, reducted glutathione Elman (7), catalase enzyme thickness Bergmeyer (8), General antioxidant activ-ity (UAF) E.V.Spector and co. (9). The experiments were divided into five groups (Table 1)
- Abbulla Oguz, Murat Kapan, Ibrahim Kaplan et al., The effects of sulforaphane on the liver and remote organ damage in hepatic Ischemia – reperfusion model formed with pringle maneuver in rats //Inter-national Journal of Surgery. 2015, N 18, p.163-168
- Ellman C., Tissue Sulfhydryle groups //Archivcs of Biochemistry and Biophysics 1959, N 1, p.70-77
- Bergmeyer H. Biochemistry Information. Methods of enzymatic analysis. Verlag Chemic
- Спектор Е.В., Ананенко А.А., Политова Л.Н. Метод определения антиокислительный активности сыворотки крови //Лаб.дело. 1984, № 1, с.26-28
- Лакин П.Ф. Биометрия М. Высшая школа. 1990, 352 с