3. The Treatment Of Anastomotic Strictures After Live-Donor Liver Transplantation

Authors

  • Y.B. Abdirashev JSC “National Scientific center of surgery named after A.N. Syzganov” Almaty, Kazakhstan
  • N.M. Abdiyev JSC “National Scientific center of surgery named after A.N. Syzganov” Almaty, Kazakhstan
  • M.O. Doskhanov JSC “National Scientific center of surgery named after A.N. Syzganov” Almaty, Kazakhstan
  • A.S. Skakbayev JSC “National Scientific center of surgery named after A.N. Syzganov” Almaty, Kazakhstan
  • A.M. Basymbekov The emergency hospital of Almaty, Kazakhstan

Downloads

Abstract

Liver transplantation is the only treatment for the decompensated level of cirrhosis. Due to improvement of the surgery methodology and management of patients, the survival rate of patients up to 1 year is 90%, and 5-year to 80%. However, post-transplantation complications remain the main cause of recipient morbid-ity and mortality. The basic reasons for the development of strictures of the bile duct after transplantation depends on: 1. The type of transplant. 2. The number and type of bile ducts carried out for the application of anastomoses, in particular liver transplantation from a living donor. 3. Type of anastomosis (biliary-biliary or choledochojejunoanastomosis). Most complications after surgery are diagnosed after live-donor liver transplantation. Since the transplant is one of the lobes with ducts of smaller diameter. Given the above, the complications of the biliary duct system after transplantation from a cadaveric donor is 5-15%, and after live-donor it reaches up to 38%. Including, when taking the right lobe of the liver in living donors, the percentage of complications varies from 24% to 60%.

Keywords

ЭРХПГ, трансплантация печени, биллиарные осложнения, биллиарная анастомотическая стриктура, билио-биллиарный анастомоз, ТПЖД, эндобил-лиарное протезирование

References

  1. Khosravi B, Pourahmad S, Bahreini A, Nikeghbalian S, Mehrdad G. Five years survival of patients after liver transplantation and its effective factors by neu-ral network and cox poroportional hazard regression models. Hepatitis 2015; 15:9
  2. Villa NA, Harrison ME. Management of biliary stric-tures after liver transplantation. Gastroenterol Hepa-tol 2015; 11:316-28
  3. Ryu CH, Lee SK. Biliary strictures after liver trans-plantation. Gut Liver 2011; 5:133-42
  4. Lee HW, Shah NH, Lee SK. An update on endoscopic management of post-liver transplant biliary compli-cations. Clin Endosc 2017; 50:451-463
  5. Guichelaar MM, Benson JT, Malinchoc M, Krom RA, Wiesner RH, Charlton MR. Risk factors for and clini-cal course of non-anastomotic biliary strictures after liver transplantation. Am J Transplant 2003; 3:885-890
  6. Pascher A, Neuhaus P. Bile duct complications after liver transplantation. Transpl Int 2005;18:627-642
  7. Linhares MM, Gonzalez AM, Goldman SM, Coelho RD, Sato NY, Moura RM, et al. Magnetic resonance cholangiography in the diagnosis of biliary complica-tions after orthotopic liver transplantation. Transplant Proc 2004; 36:947-948
  8. Meersschaut V, Morteleґ KJ, Troisi R, Van Vlierber-ghe H, De Vos M, Defreyne L, et al. Value of MR chol-angiography in the evaluation of postoperative biliary complications following orthotopic liver transplanta-tion. Eur Radiol 2000;10:1576-1581
  9. Akamatsu N, Sugawara Y, Hashimoto D. Biliary re-construction, its complications and management of biliary complications after adult liver transplantation: a systematic review of the incidence, risk factors and outcome. Transpl Int. 2011;24:379–92
  10. Sharma S, Gurakar A, Jabbour N. Biliary strictures following liver transplantation: past, present and pre-ventive strategies Liver Transpl. 2008;14:759–69
  11. Mahajani RV, Cotler SJ, Uzer MF. Efficacy of endo-scopic management of anastomotic biliary stric-tures after hepatic transplantation. Endoscopy 2000;32:943-949
  12. Rossi AF, Grosso C, Zanasi G, Gambitta P, Bini M, De Carlis L, et al. Long-term efficacy of endoscopic stenting in patients with stricture of the biliary anas-tomosis after orthotopic liver transplantation. Endos-copy 1998; 30: 360-366
  13. Morelli J, Mulcahy HE, Willner IR, Cunningham JT, Draganov P. Long-term outcomes for patients with post-liver transplant anastomotic biliary strictures treated by endoscopic stent placement. Gastrointest Endosc 2003;58: 374-379
  14. Itoi T, Yamanouchi E, Ikeuchi N, Kasuya K, Iwamoto H, Tsuchida A. Magnetic compression duct-to-duct anastomosis for biliary obstruction in a patient with living donor liver transplantation. Gut Liver 2010;4 Supplement 1:S96-S98
  15. Dumonceau JM, Tringali A, Blero D, et al; European Society of Gastrointestinal Endoscopy. Biliary stent-ing: indications, choice of stents and results: Euro-pean Society of Gastrointestinal Endoscopy (ESGE) clinical guideline. Endoscopy 2012; 44:277-298
  16. Chathadi KV, Chandrasekhara V, Acosta RD, et al; ASGE Standards of Practice Committee. The role of ERCP in benign diseases of the biliary tract. Gastro-intest Endosc 2015; 81:795-803
  17. Biliary stenting: Indications, choice of stents and results: European Society of Gastrointestinal Endos-copy (ESGE) clinical guideline Endoscopy 2012; 44: 277–292
  18. Tringali A, Barbaro F, Pizzicannella M, Boškoski I, Fa-miliari P, Perri V, et al. Endoscopic management with multiple plastic stents of anastomotic biliary stricture following liver transplantation: long-term results. En-doscopy 2016; 48: 546-51
  19. Prophylaxis of post-ERCP pancreatitis: European So-ciety of Gastrointestinal Endoscopy (ESGE) Guideline – Updated June 2014 Endoscopy 2014; 46: 799–815
  20. Morelli J, Mulcahy HE, Willner IR, Cunningham JT, Draganov P. Long-term outcomes for patients with post-liver transplant anastomotic biliary strictures treated by endoscopic stent placement. Gastrointest Endosc 2003;58: 374-379
  21. Schwartz DA, Petersen BT, Poterucha JJ, Gostout CJ. Endoscopic therapy of anastomotic bile duct strictures occurring after liver transplantation. Gas-trointest Endosc 2000;51:169-174
  22. Hsieh TH, Mekeel KL, Crowell MD, et al. Endoscopic treatment of anastomotic biliary strictures after living donor liver transplantation: outcomes after maximal stent therapy. Gastrointest Endosc. 2013;77:47–54
  23. Kawano Y, Mizuta K, Hishikawa S, et al. Rendezvous penetration method using double-balloon endoscopy for complete anastomosis obstruction of hepaticoje-junostomy after pediatric living donor liver transplan-tation. Liver Transpl. 2008;14:385–7
  24. Bing Hu, Bo Sun, Qiang Cai et.al Asia-Pacific con-sensus guidelines for endoscopic management of benign biliary strictures. Gastrointestinal Endoscopy Volume 86, No. 1 : 2017

Published

2020-07-01

Section

Статьи