2. PANCREATIC CANCER DIAGNOSIS OVERCOMING BIAS AND ERRORS (CASE SERIES)
DOI:
https://doi.org/10.35805/BSK2024II002Downloads
Abstract
Diagnosing malignant pancreatic neoplasms presents a challenging task fraught with the possibility of diagnostic errors due to similarities with other pathologies such as pancreatitis, neuroendocrine tumors, and cystic formations. The key diagnostic method is contrast-enhanced multi-detector computed tomography, yet even this method has certain limitations that may affect diagnostic accuracy.Through the analysis of clinical cases, typical errors accompanied by visual characteristics that can be misleading in differential diagnosis have been identified. Hypodensity and tissue structure alterations, changes in ducts, or mass effect may be common features of both cancer and pancreatitis. Comparing visual signs with the clinical picture and employing additional methods aids in reaching a more precise diagnosis.It is important to note that rare pathologies such as serous oligocystic adenoma and intraductal papillary mucinous neoplasm may also pose additional challenges for accurate diagnosis due to their unusual characteristics on computed tomography scans.The conclusions of the study underscore the importance of a multimodal approach to diagnosing malignant pancreatic neoplasms, including the use of various imaging methods to ensure an accurate diagnosis and the selection of the most appropriate treatment strategy
Keywords
—
References
- Haj-Mirzaian A, Kawamoto S, Zaheer A, Hruban RH, Fishman EK, Chu LC. Pitfalls in the MDCT of pancreatic cancer: strategies for minimizing errors. Abdom Radiol (NY). Feb 2020;45(2):457-478. doi:10.1007/ s00261-019-02390-9
- StatPearls. 2024. BIAS AND ERRORS (CASE SERIES)
- Reznek RH. CT/MRI of neuroendocrine tumours. Cancer Imaging. Oct 31 2006;6(Spec No A):S163-77. doi:10.1102/1470-7330.2006.9037
- Choi JY, Kim MJ, Lee JY, et al. Typical and atypical manifestations of serous cystadenoma of the pancreas: imaging findings with pathologic correlation. AJR Am J Roentgenol. Jul 2009;193(1):136-42. doi:10.2214/ AJR.08.1309
- Morgan DE, Waggoner CN, Canon CL, et al. Resectability of pancreatic adenocarcinoma in patients with locally advanced disease downstaged by preoperative therapy: a challenge for MDCT. AJR Am J Roentgenol. Mar 2010;194(3):615-22. doi:10.2214/ AJR.08.1022
- Fouladi DF, Raman SP, Hruban RH, Fishman EK, Kawamoto S. Invasive Intraductal Papillary Mucinous Neoplasms: CT Features of Colloid Carcinoma Versus Tubular Adenocarcinoma of the Pancreas. AJRAmJRoentgenol. May 2020;214(5):10921100. doi:10.2214/AJR.19.21824
- Пантелеев В, Горин Д, Калдаров А, Кригер А. Внутрипротоковая папиллярная муцинозная опухоль поджелудочной железы. Хирургия Журнал им НИ Пирогова. 2019;11:81-87. {PanteleyevV, GorinD, KaldarovA, KrigerA. Vnutriprotokovayapapillyarno-mutsinoznayaopukhol' podzheludochnoyzhelezy. Khirurgicheskiyzhurnalim. N. I. Pirogova. 2019;11:81-87.}
- Белоусова ЕЛ, Кармазановский ГГ, Кубышкин ВА, etal. КТпризнаки, позволяющие определить оптимальную тактику лечения при нейроэндокринных опухолях поджелудочной железы. Медицинская визуализация. 2015;(5):73-82. {BelousovaYe.L., KarmazanovskiyG.G., KubyshkinV.A. idr. KT-priznaki, pozvolyayushchiyeopredelit' optimal'nuyutaktikulecheniyaneyroendokrinnykhopukholeypodzheludochnoyzhelezy. Meditsinskaya vizualizatsiya. 2015;(5):73-82}