T. Taukelova Ainur

https://orcid.org/0000-0002-4237-9835

Articles found: 2

  • Six-Minute Walk Test As A Tool For Assessing Physical Activity In Patients With Heart Failure (Issue № 3, 2025)

    S. Bekbossynova Makhabbat, R. Kushugulova Almagul, K. Jetybayeva Saltanat, T. Tauekelova Ainur, S. Duisenbina Zhadyra, Aida Zholdybaeva
    2025-09-30
    64–72
    Abstract

    Background. Heart failure is one of the most significant medical problems of our time, which is associated with the increase in the prevalence of the disease over the past decade. The six-minute walk test is a simple, accessible, and informative tool for assessing the physical activity of patients with heart failure. The test results correlate with peak oxygen consumption and can be used to monitor the effectiveness of rehabilitation programs. The aim of the study is to evaluate the effectiveness of the six-minute walk test as a tool for measuring the level of physical activity and functional status in patients with heart failure, and to determine its correlation with clinical indicators and quality of life in this category of patients.

    Materials and methods. In this study, conducted on the basis of the UMC "Heart Center" Astana, Kazakhstan, private institution "National Laboratory Astana", data of patients with heart failure of class I-IV according to a special classification were analyzed. The main objective of the study was to evaluate the effectiveness of the test as a tool for monitoring physical activity and functional status of patients.

    Results. The results showed that the test is a reliable method for assessing the dynamics of physical capabilities and can be used to individualize rehabilitation programs.

    Conclusion. The 6MWT remains an important component of clinical practice, helping to optimize functional outcomes and improve the quality of life of patients with heart failure.

    Keywords

    functional status, quality of life, cardiac rehabilitation, physical activity, six-minute walk test (6MWT), heart failure

  • Periodontitis As A Possible Cause Of Chronic Heart Failure (Issue № 3, 2025)

    Dana Yessimgalikyzy, R. Aipov Baurzhan, R. Kassiyet Nurlan, Aldanysh Zhumazhan, T. Taukelova Ainur, K. Saltanat, Islambek Laiskanov, Aliya Sailybayeva, S. Bekbosynova Makhabbat, R. Kushugulova Almagul
    2025-09-30
    56–63
    Abstract

    Background. The objective of this study was to investigate the prevalence of periodontitis in patients with chronic heart failure, as well as to characterize the microbiological profile of periodontitis across different chronic heart failure phenotypes. The objective is to analyze the link between oral health and heart disease.

    Materials and Methods. A cohort of 98 chronic heart failure patients (mean age 62.22 ± 8.62 years, 69 men) was assessed through comprehensive cardiological and periodontal examinations. Patients were categorized into heart failure with reduced ejection fraction, mildly reduced ejection fraction, and preserved ejection fraction. Periodontal parameters, including probing pocket depth, clinical attachment loss, and bleeding on probing were evaluated. Microbiological and statistical analyses were conducted.

    Results. Severe periodontitis (Stage C) was identified in 30% of patients, while 48% had moderate periodontitis (Stage B). Patients with chronic heart failure with reduced ejection fraction exhibited the highest prevalence of severe periodontitis, with a significant correlation between increased probing pocket depth and reduced ejection fraction. Candida species abundance was associated with lower ejection fraction (p≤0.0Y) and advanced periodontitis (p≤0.0X). Elevated NT-proBNP levels (1121.00–7611.00 pg/mL) correlated with Streptococcus mitis prevalence, while C-reactive protein levels (up to 2.35 mg/dL) were highest in patients with Klebsiella pneumoniae.

    Conclusion. The study highlights a strong association between periodontal disease, microbial dysbiosis, and CHF. Findings suggest that oral microbial imbalances, particularly involving Candida, Streptococcus mitis, and Klebsiella pneumoniae, contribute to systemic inflammation and cardiovascular complications.

    Keywords

    dental health surveys, gingiva pathology, heart failure, inflammation, periodontal index