3. Choice Of Pulmonary Resections In Intrathoracic Tumors: Short-Term Outcomes

Authors

  • V. Makarov Al-Farabi Kazakh National University, Almaty, Kazakhstan, Almaty Oncology Center, Almaty, Kazakhstan
  • E. Baimukhametov Kazakh Medical University of Continuing Education, Almaty, Kazakhstan
  • S. Yessentayeva Kazakh-Russian Medical University, Almaty, Kazakhstan
  • Zh. Kalmatayeva Al-Farabi Kazakh National University, Almaty, Kazakhstan
  • R. Kadyrbayeva Kazakh Institute of Oncology and Radiology, Almaty, Kazakhstan
  • A. Semenova Almaty Oncology Center, Almaty, Kazakhstan
  • N. Baltaev Almaty Oncology Center, Almaty, Kazakhstan
  • R. Irsaliev Almaty Oncology Center, Almaty, Kazakhstan
  • A. Orazbaev Almaty Oncology Center, Almaty, Kazakhstan

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Abstract

Relevance:Lung cancer still leads in morbidity and mortality among other cancers. In 2018, 2.094 million new lung cancer cases and 1.8 million deaths from lung cancer were registered globally. The study aimed to evaluate the effectiveness of surgical treatment for lung cancer depending on the extent of surgery. Material and

Methods: The article provides a retrospective analysis of 137 patients operated for lung cancer at Almaty Oncology Center in 2014-2018. The database was created in Microsoft Excel. IBM SPSS Statistics, package 19 (trial version) mathematical data processing software was used for statistical processing. The survival rate was measured from the commencement of treatment till the patient’s death for any reason or to the last observation date. The cut-off date was January 1, 2019.

Results: Most of the patients (91/137, 69.3%) had a locally advanced Stage IIb-IIIb process. Localized forms of the disease were diagnosed in 21.1% of cases. R0 resection was achieved in 83.9%, R1 – 13.1%, R2 – 2.9% of patients. The post-surgery mortality amounted to5.8%. One-year survival amounted to 70% SE4 for lobectomy, 87% SE9 for segmental resections, 79% SE8 for bronchoplastic, lobar resections, and 67% SE10 for pneumonectomy. The difference in median survival was statistically significant: χ2 = 9.7, р = 0.045.

Conclusion: We consider the extent of surgery a risk factor. The organ ectomies should be minimized since our data and the literature report high one-year mortality and low 5-year survival after such surgeries.

Keywords

lung cancer, lung cancer surgery, lobectomy, pneumonectomy, sleeve lobectomy, segmentectomy

References

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Published

2021-05-21

Issue

No. 1 (2021)

Section

Статьи