М. Baurzhan

https://orcid.org/0000-0003-1244-8673

Articles found: 2

  • Clinical case of monostotic fibrous dysplasia in a child (Issue № 1, 2025)

    D. Autalipov, A. Bekpan, N. Sagandykova, M.. Baurzhan
    2025-03-31
    14–19
    Abstract

    Fibrous dysplasia is a rare tumor-like condition characterized by the replacement of normal bone with fibrous tissue, with an etiology of uncertain origin. Diagnosis relies on clinical and radiological data, with biopsies used in doubtful cases. The aim of our study is to demonstrate our experience in working with a rare pathology such as fibrous dysplasia of the pterygoid process. We report a clinical case of isolated fibrous dysplasia affecting the pterygoid process of the left sphenoid bone, treated in the Pediatric Head and Neck Surgery Department of the University Medical Center, Astana, Kazakhstan. The patient, a 15-year-old girl, presented with a diagnosis of fibrous osteodysplasia of the left pterygoid process of the sphenoid bone. As a result of surgical treatment, we did not observe an increase in the tumor during a 3-year follow-up. Diagnosis of some tumors, such as fibrous dysplasia, is difficult and requires modern diagnostic methods. The presence of fibrous dysplasia in the sphenoid bone is a caustic pathology, which makes this clinical case unique. In this case, we used transnasal endoscopic approaches, which demonstrated the effectiveness of the treatment.

    Keywords

    fibrous dysplasia, tumor-like process, children, histiocytosis, bone tissue lesion

  • Modern biomarkers - predictors of earlycardiovascular ageing (literature review) (Issue № 1, 2024)

    M. Abdykassymova, K. Abzaliyev, Ghazwan Butrous, S. Abzaliyeva, A. Kurmanova, R. Bitemirova, D. Sundetova, U. Sagalbayeva, A. Bugibayeva, N. Baizhigitova, A. Kenzhebaeva, М. Baurzhan
    2024-05-21
    4–11
    Abstract

    An analysis of the current state of the problem of studying biomarkers of human cardiovascular ageing was carried out based on an analysis of international experience. Ageing is an inevitable, constantly progressive systemic process, which is a significant risk factor for the development of most common chronic human diseases, including cardiovascular diseases. Therefore, studying markers of early cardiovascular ageing is a logical goal for developing measures to prevent the development of cardiovascular disease and toimprove the quality of life and prolong active longevity. the intensive care unit. The application of a multidisciplinary approach to diagnose and treat a life-threatening complication as tracheal rupture in a short time allowed us to stabilize the patient’s condition and avoid the development of further complications.

    Keywords

    biomarkers of ageing, predictors of cardiovascular ageing, theories of ageing, regulation of ageing, longevity