5. Prognostic value of urinary albumin-to-creatinine ratio in a surgical practice

Abstract

Background. The urinary albumin-to-creatinine ratio is a well-established marker RI early kidney damage endothelial dysfunction and systemic LQʗammation (levated urinary albumin-to-creatinine ratio levels are linked to increased cardiovascular risk and mortality 'uring surgical stress urinary albumin WR creatinine ratio may UHʗect vascular and LQʗammatory changes yet its prognostic value LQ surgical patients remains insufʖciently studied Objective 7R assess the prognostic signiʖcance RI urinary DOEXmin-to-creatinine ratio in patients undergoing surgical interventions. Materials and

Methods. A retrospective analysis included 171 patients (98 men, 73 women aged ɇ years who underwent various surgeries DW the National ScientiʖF Center of Surgery named after ^KkK Syzganov from March 2022 to March 2025. Random morning urine samples were analyzed for albumin and creatinine, and urinary albumin-to-creatinine ratio was calculated. Measurements were performed using Cobas 303 and 311 analyzers (Roche Diagnostics).

Results. The mean age was 53.2 years. Mean urinary creatinine and albumin were mmol / and PJ / with median values RI mmol / and PJ / respectively Median urinary albumin WR creatinine ratio was PJ mmol mean was PJ mmol indicating skewness 1R signiʖcant correlation was found between albumin and creatinine ƣ ɇ S $ moderate non signiʖcant inverse correlation was observed LQ the high level subgroup Q

Conclusion. Although overall correlations were not signiʖcant ʖndings suggest that urinary albumin-to-creatinine ratio may have prognostic potential. Further prospective studies are needed, especially in abdominal surgery settings. '2, %6. ,, Aubakirova A.