4. Hemodynamic Changes Due To Pulmonectomy (Experimental Study)

Authors

  • M.T. Nadyrov National Medical University named after S.D. Asfendiyarova, Almaty, Kazakhstan
  • A.N. Baymakhanov National Medical University named after S.D. Asfendiyarova, Almaty, Kazakhstan
  • I.A. Almabayev National Medical University named after S.D. Asfendiyarova, Almaty, Kazakhstan
  • A.A. Orazbek National Medical University named after S.D. Asfendiyarova, Almaty, Kazakhstan
  • L.P. Deryabin National Medical University named after S.D. Asfendiyarova, Almaty, Kazakhstan

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Abstract

Relevance. Currently, the main directions of treatment of postoperative disorders after pulmonectomy are infusion-transfusion maintenance of hemodynamics, antibacterial chemoprophylaxis of infectious com-plications and perioperative nutritional support. An analysis of the literature data showed that the severity and originality of the course of the postoperative period is determined by hemodynamic disturbances and the function of vital organs, which determines the relevance of this problem..

Materials and methods. The study was conducted on 12 laboratory animals (rabbits). The state of the pulmonary artery, pulmonary tissue and portal blood flow was studied by radioisotope method from the moment of pulmonary artery ligation up to one month after pulmonectomy. Hemodynamics was evaluated after 1 and 3 hours, 1; 3 and 7 days and a month later..

Results. Removal of one lung significantly disrupts the hemodynamics of the remaining lung, which occurs during ligation of the pulmonary artery. Violation of pulmonary blood flow, in turn, leads to a violation of the portal-venous blood flow that occurs during blinking of the bronchi, and a violation of local blood flow is recorded 3 hours after pulmonectomy.

Keywords

Pulmonectomy

References

  1. Phillips B, Turco L, Mirzaie M, Fernandez C. Trauma pneumonectomy: A narrative review. Int J Surg. 2017 Oct; 46: 71-74. doi:10.1016/j.ijsu.2017.08.08.570.Epub2017Aug31.Review
  2. Drinhaus H, Doerr F, Hekmat K. Heart in the Wrong Place: Cardiac Herniation after Pulmonectomy. Dtsch Arztebl Int. 2018 Apr 6; 115 (14): 249. doi:10.3238/arztebl.2018.0249a
  3. Wang K, Wang J , Wei F, Zhao N, Yang F, Ren X. Ex-pression of TLR4 in Non-Small Cell Lung Cancer Is Associated with PD-L1 and Poor Prognosis in Patients Receiving Pulmonectomy. Front Immunol. 2017Apr 21;8:456. doi:10.3389/fimmu.2017.00.00456.eCol-lection2017
  4. Hanuliak J, Szkorupa M, Chudacek J, Stasek M, Neoral C. Combined treatment of early tracheobron-chopleural fistula after right tracheal sleeve pneumo-nectomy Rozhl Chir. Summer 2017; 96 (5): 213-217
  5. Motus IY, Bazhenov AV, Tsvirenko AS, Basyrov RT, Kholny PM, Kardapoltsev LV, Pechnikov PP. Bron-chial fistula management. Is the exit found? Khirur-giia (Mosk). 2018; (3. Vyp. 2): 33-38. doi:10.17116/hirurgia20183233-38
  6. Rivera S, Crane MM, McManamon R, Gregory CR. Surgical treatment of pulmonary melanophoroma in a beaded lizard (heloderma horridum exaspera-tum. J Zoo Wildl Med. 2015 Jun; 46 (2): 397-9. doi:10.1638/2014-0188R2.1.(EXPERIMENTALSTUDY)

Published

2019-10-01

Issue

No. 3 (2019)

Section

Статьи