8. Detection Of Cmv Infection By Biopsy In Recipients With Kidney Graft Dysfunction
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Abstract
Kidney transplantation is the most effective and preferable treatment option of terminal stage of chronic kidney disease. Nowadays kidney transplantation is well-developed modality and early graft and patient survival rates overall the world greatly increased. But improvement of graft and patient survival rates in long-term period remains to be problem. Beside the immunologic factors that causes either acute or chronic graft rejection, there are another etiologic factors of graft rejection. Infections, particularly wide-spread in solid organ recipients - cytomegalovirus infection (CMV), appears to be one of this etiologic factors. Mechanism of injury of graft by cytomegalovirus remains to be unclear. Diagnostics of CMV is also a difficult. objective. In our institution we conducted an investigation aimed the detection of CMV by graft biopsy in patients with graft dysfunction. The main objective of this investigation is the demonstration of efficacy of biopsy in diag-nostics of CMV infection in graft dysfunction.
Keywords
cytomegalovirus, graft dysfunction, biopsy, kidney transplantation
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