6. Comparative evaluation of a controlled clinical test of apparatus intraoperative reinfusion of blood collected from the pleural cavity under slow and fast modes
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Abstract
Objective. An analysis of the study, in the mode of fast and slow blood exfusion, controlled clinical trials showed that the number of platelets was significantly reduced.
Material and methods. We have conducted a series of researches in 44 patients with cavitary blood loss, which is 34.3% of the total number of the examined patients (n-128), for whom an IOBR apparatus technology was used. The studies were also conducted during the surgery in the first 2 hours.
Results. Controlled clinical trials (CCT) have shown that blood exfusion after intraoperative blood reinfusion, the degree of destruction of erythrocytes and leukocytes with slow blood exfusion is 35%, and with fast - 48%. Osmotic resistance is reduced by 3 times. With rapid hardware exfusion, blood hemolysis is more than 28%, which should be taken into account when performing hardware intraoperative blood reinfusion. Controlled clinical trials have shown that the faster the machine exfusion is performed, the greater the decrease in protein and bilirubin content. In the blood collected in the mode of rapid apparatus exfusion, a higher concentration of K +, residual N and urea is noted. Controlled clinical trials have shown that platelet counts are significantly reduced, especially when using a rapid blood collection regimen. Against this background, the process of aggregation is reliably slowed down, and with a fast mode of blood collection - 2 times in comparison with the control. Plasma recalcification time is reliably reduced by 40% when using a high-speed blood collection mode in comparison with the control values, which is almost 3 times higher than when using slow blood aspiration.
Conclusion. The article provides an analysis of scientific research, CCT, experimental control, clinical control and practical work. The work is interdisciplinary in nature, written at the intersection of surgery and anesthesiology, to increase the effectiveness of emergency surgery and anesthesiology-resuscitation in critical abdominal and luminal blood loss based on the optimization of intraoperative infusion-transfusion therapy.
Keywords
controlled clinical trials, instrumental intraoperative blood reinfusion, pleural cavity
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